Biomarkers Predictive of Therapeutic Benefit 4

• 3729 · PDF 一种基于肿瘤转录组学和组织病理学、具有生物学基础的乳腺癌新辅助治疗反应预测因子 A biologically grounded predictor of neoadjuvant breast cancer therapy response from tumor transcriptomics and histopathology Thomas Cantore, Danh-Tai Hoang, Lipika Ray, Amos Stemmer, Tiangen Chang, Saugato Rahman Dhruba, Eldad David Shulman, Emma M. Campagnolo, Joo Sang Lee, Salomon M. Stemmer, Stephen-John Sammut, Yuan Yuan, Stan Lipkowitz, Sheila Rajagopal, Carlos M. Caldas, Nishanth Ulhas Nair, Eytan Ruppin
• 3730 · PDF 非小细胞肺癌（NSCLC）患者免疫治疗敏感性中 TILs 的空间决定因素 Spatial determinants of TILs in immunotherapy sensitivity of patients with non-small cell lung cancer (NSCLC) Miguel Lopez de Rodas Gregorio, Ravi Kamble, Matthew Blair, Yao Nie, Marghoob Mohiyuddin, Sowmi Utiramerur, Kurt Alex Schalper
• 3731 · PDF 贝伐珠单抗反应基因表达预测因子的开发 Development of a gene expression predictor for bevacizumab response Yi Ren, Chee Yit Lim, Yaw Chyn Lim, Joseph W. Foley, Raymond Tsang, Wan Qin Chong, Boon Cher Goh, Joshua K. Tay
• 3732 · PDF 用于预测非小细胞肺癌放疗后肋骨骨折的时间序列深度学习影像组学 Time-series deep learning radiomics for predicting post-radiotherapy rib fractures in non-small cell lung cancer Yijun Chen, Michael Farris, Ariel Choi, Nga Thi Thanh Nguyen, Amanda Goetz, Corbin A. Helis, Fei Xing, Liang Liu, Qing Lyu, Christopher T. Whitlow, Christina K. Cramer, Michael D. Chan, Dan Bourland, Michael T. Munley, Jeffrey S Willey, Yuming Jiang
• 3733 · PDF 优化基于NGS的错配修复与校对缺陷生物标志物 Optimizing NGS-based biomarkers for mismatch repair and proofreading deficiency Jan Budczies, Klaus Kluck, Michael Menzel, Daniel N. Kazdal, Matthias Kloor, Albrecht Stenzinger
• 3734 · PDF 早发低级别不良事件作为晚期NSCLC的预测性生物标志物:一项多治疗队列分析 Early-onset low-grade adverse events as predictive biomarkers in advanced NSCL: A multi-treatment cohort analysis Dung-Tsa Chen, Andreas N. Saltos, Zachary Thompson, Junmin Whiting, Sebastian Viracacha, Timothy I. Shaw, Ignacio I. Wistuba, Jhanelle E. Gray
• 3735 · PDF Septin9亚型作为乳腺癌紫杉烷类反应的生物标志物 Septin9 isoforms as biomarkers of taxane response in breast cancer Jycole E. M. Bush, Jacob Essif, KATE LATHROP, April Risinger
• 3736 · PDF C3C:细胞外组织蛋白酶活性与ADC的生物标志物 C3C: A biomarker for extracellular cathepsin activity and ADCs Marina Crespo-Bravo, Nicholas Willumsen, Morten Karsdal
• 3737 · PDF BXQ-350:一种靶向失调鞘脂代谢并使新诊断转移性结直肠癌患者(mCRC)关键抗肿瘤和促肿瘤鞘脂正常化的新型生物制剂 BXQ-350: A novel biologic that targets dysregulated sphingolipid metabolism and normalizes key anti-tumoral and pro-tumoral sphingolipids in newly diagnosed metastatic colorectal carcinoma patients (mCRC) Gilles H. Tapolsky, TARIQ ARSHAD, Michael Gazda, Jackson Bond, Nikhil Wilkins, James Beach
• 3738 · PDF TAG-72(一种基于聚糖的ADC靶点)的表征及其泛肿瘤表达谱 Characterization of TAG-72, a glycan-based ADC target and its pan-tumor expression profile Joseph D. Schonhoft, Martijn H. den Brok, Marleen H. van Stevendaal, Thaddeus J. Unger, Lieke W. Wouters, Luc M. Zijlmans, Renate van Daalen, Raffaella Rossin, Marc Robillard, Keith Orford
• 3739 · PDF 胰腺癌来源小细胞外囊泡的分离与表征:一种新型液体活检方法 Isolation and characterization of pancreatic cancer-derived small extracellular vesicles as a novel liquid biopsy approach Ravi Kumar Paluri, Ashish Kumar, Yixin Su, Gregory L. Kucera, Ashish Manne, Jingyun Lee, Sangeeta Sing, Susy Kim, Cristina Furdui, Gagan Deep
• 3740 · PDF OncoGraph:一种利用蛋白标志物监测癌症复发和治疗反应的患者特异性血液检测 OncoGraph: A patient-specific blood test using protein markers to monitor cancer recurrence and treatment response Mao Mao, Wenjian Wang, Qingqi Ren, Shiyong Li, Wei Wu
• 3741 · PDF 放疗-树突状细胞联合疗法驱动肝癌全身细胞免疫的改变 Radiation-dendritic cell combination therapy drives systemic cellular immune shifts in liver cancer Melody Wu, Panwen Wang, Chen Wu, Ying Li, Christopher L. Hallemeier, Thomas D. Atwell, Nguyen H. Tran, Andre de Menezes Silva Corraes, Kevin Regan, Zuoyi Shao, Rayaan Kamal, Haidong Dong, Lewis R. Roberts, Sean Park, Yi Lin, Lionel Aurelien Kankeu Fonkoua
• 3742 3742 在11q13扩增的中国食管癌中，免疫微环境而非基因组改变驱动超进展相关特征 Immune microenvironment rather than genomic alterations drives hyperprogression-related features in 11q13 amplified Chinese esophageal cancer Ling Deng
• 3743 · PDF ddPLEX EGFR/KRAS/BRAF：一种用于超灵敏NSCLC生物标志物检测的高度多重微滴式数字PCR(ddPCR)panel ddPLEX EGFR/KRAS/BRAF: A highly multiplexed droplet digital PCR (ddPCR) panel for ultra-sensitive NSCLC biomarker detection Surbhi Jain, Cailin Festog, Mai Ho, Cindy Li, Necip Mehmet, Ady Melendez-Molina, Toshiro Newsum, Prithwish Pal, Mina Rostamza, Yusuke Ono, Leisa Jackson, Brittany D’Alessio, Gunnar Johnson, Gary A. Pestano
• 3744 · PDF 外周免疫指标预测炎性乳腺癌的病理完全缓解和残余癌负荷 Peripheral immune indices predict pathologic complete response and residual cancer burden in inflammatory breast cancers Hui Gao, Ranjan Upadhyay, Angela Alexander, Angela N. Marx, Megumi Kai, Chelain R. Goodman, Azadeh Nasrazadani, Savitri Krishnamurthy, Anthony Lucci, Rachel M. Layman, Sadia Saleem, Vicente Valero, Michael C. Stauder, Susie X. Sun, Gary J. Whitman, Miral M. Patel, Huong C. Le-Petross, Chasity L. Yajima, Lily Villarreal, Heather Lopez, Bora Lim
• 3745 · PDF 利用单核多组学揭示与局部晚期疾病相关的透明细胞肾细胞癌异质性 Unveiling clear cell renal cell carcinoma heterogeneity associated with locally advanced disease using single nucleus multi-omics Pratik Shah, Anita Ng, Justin Wang, Houman Khalili, Tony Pham, Melissa Neumann, Xinhua Zhu, Annette Lee, Andrew Shih
• 3746 · PDF 接受PSCA靶向CAR-T细胞治疗的mCRPC中的单细胞液体活检分析 Single-cell liquid biopsy profiling in mCRPC receiving PSCA-targeted CAR-T cell therapy Doanna Minh Pham, Stephanie Nicole Shishido, Saul J. Priceman, Tanya B. Dorff, Peter Kuhn
• 3747 · PDF 利用FFPE肿瘤的Hi-C测序发现并功能性表征NSCLC中的增强子劫持致癌基因重排 Discovery and functional characterization of enhancer hijacking oncogene rearrangements in NSCLC using Hi-C sequencing of FFPE tumors Kristin Sikkink, Blake Skrable, Sid Selvaraj, Alex Hastie, Anthony Schmitt
• 3748 · PDF 肺鳞状细胞癌中共享突变的比例提供了可指导治疗方法的洞见 A proportion of shared mutations in lung squamous cell carcinoma provides insights that may guide therapeutic approaches Jaewoong Lee, Jun Hyeok Lim, Lucia Kim, Woo Kyung Ryu, Hyun-Tae Shin, In-Jae Oh, Sabin Park, Yoo Duk Choi, Semin Lee, Jeong Seon Ryu
• 3749 · PDF 整合多组学与功能研究以鉴定不同AML亚型中AOH1996敏感性的生物标志物 Integrative multiomics and functional studies to identify biomarkers of AOH1996 sensitivity across AML subtypes Hamsini Kala, Dana Abou Abbas, Robert J. Hickey, Linda H. Malkas, Caroline M. Li, Robert G. Lingeman, Guido Marcucci, Le Xuan Truong Nguyen, Brian Ball, Amanda Blackmon, Melissa Ronan, Jennifer Roth, Matthew G. Rees
• 3751 · PDF QVT亚评分：一个可解释的肿瘤血管性放射组学面板揭示NSCLC中治疗特异性作用机制（MoA） QVT Subscore: An interpretable radiomic panel of tumor vascularity reveals treatment-specific mechanisms-of-action (MoA) in NSCLC Haojia Li, Pushkar Mutha, Young Kwang Chae, Kai Zhang, Liam Il-Young Chung, Amogh Hiremath, Rhea Chitalia, Justin Yau, Omid Haji-Maghsoudi, Trishan Arul, Vamsidhar Velcheti, Anant Madabhushi, Nathaniel Braman
• 3752 · PDF RNA编辑脱氨酶激活作为追踪造血干细胞适应性与白血病演化的动态标志物 RNA editing deaminase activation as a dynamic marker to track hematopoietic stem cell fitness and leukemia evolution Inge van der Werf, Jessica Pham, Neha Katragadda, Kendale Wirtjes, Athena Mohebbi, Emma Klacking, Thomas Whisenant, Ludmil B. Alexandrov, Sheldon Morris, Catriona Jamieson
• 3753 · PDF 揭示肺癌免疫治疗反应的肿瘤微生物和免疫生物标志物 Uncovering tumor microbial and immune biomarkers of immunotherapy response in lung cancer Lili Ma, Chao Cheng, Shwetha Vasanth Kumar, Spiridon Tsavachidis, Aaron P. Thrift, Joseph F. Petrosino, Hee-Jin Jang, Robert Taylor Ripley, Christopher I. Amos, Hyun-Sung Lee, Matthew B. Schabath, David C. Christiani, Yanhong Liu

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