Biomarkers Predictive of Therapeutic Benefit 4

• 3729 · PDF A biologically grounded predictor of neoadjuvant breast cancer therapy response from tumor transcriptomics and histopathology Thomas Cantore, Danh-Tai Hoang, Lipika Ray, Amos Stemmer, Tiangen Chang, Saugato Rahman Dhruba, Eldad David Shulman, Emma M. Campagnolo, Joo Sang Lee, Salomon M. Stemmer, Stephen-John Sammut, Yuan Yuan, Stan Lipkowitz, Sheila Rajagopal, Carlos M. Caldas, Nishanth Ulhas Nair, Eytan Ruppin
• 3730 · PDF Spatial determinants of TILs in immunotherapy sensitivity of patients with non-small cell lung cancer (NSCLC) Miguel Lopez de Rodas Gregorio, Ravi Kamble, Matthew Blair, Yao Nie, Marghoob Mohiyuddin, Sowmi Utiramerur, Kurt Alex Schalper
• 3731 · PDF Development of a gene expression predictor for bevacizumab response Yi Ren, Chee Yit Lim, Yaw Chyn Lim, Joseph W. Foley, Raymond Tsang, Wan Qin Chong, Boon Cher Goh, Joshua K. Tay
• 3732 · PDF Time-series deep learning radiomics for predicting post-radiotherapy rib fractures in non-small cell lung cancer Yijun Chen, Michael Farris, Ariel Choi, Nga Thi Thanh Nguyen, Amanda Goetz, Corbin A. Helis, Fei Xing, Liang Liu, Qing Lyu, Christopher T. Whitlow, Christina K. Cramer, Michael D. Chan, Dan Bourland, Michael T. Munley, Jeffrey S Willey, Yuming Jiang
• 3733 · PDF Optimizing NGS-based biomarkers for mismatch repair and proofreading deficiency Jan Budczies, Klaus Kluck, Michael Menzel, Daniel N. Kazdal, Matthias Kloor, Albrecht Stenzinger
• 3734 · PDF Early-onset low-grade adverse events as predictive biomarkers in advanced NSCL: A multi-treatment cohort analysis Dung-Tsa Chen, Andreas N. Saltos, Zachary Thompson, Junmin Whiting, Sebastian Viracacha, Timothy I. Shaw, Ignacio I. Wistuba, Jhanelle E. Gray
• 3735 · PDF Septin9 isoforms as biomarkers of taxane response in breast cancer Jycole E. M. Bush, Jacob Essif, KATE LATHROP, April Risinger
• 3736 · PDF C3C: A biomarker for extracellular cathepsin activity and ADCs Marina Crespo-Bravo, Nicholas Willumsen, Morten Karsdal
• 3737 · PDF BXQ-350: A novel biologic that targets dysregulated sphingolipid metabolism and normalizes key anti-tumoral and pro-tumoral sphingolipids in newly diagnosed metastatic colorectal carcinoma patients (mCRC) Gilles H. Tapolsky, TARIQ ARSHAD, Michael Gazda, Jackson Bond, Nikhil Wilkins, James Beach
• 3738 · PDF Characterization of TAG-72, a glycan-based ADC target and its pan-tumor expression profile Joseph D. Schonhoft, Martijn H. den Brok, Marleen H. van Stevendaal, Thaddeus J. Unger, Lieke W. Wouters, Luc M. Zijlmans, Renate van Daalen, Raffaella Rossin, Marc Robillard, Keith Orford
• 3739 · PDF Isolation and characterization of pancreatic cancer-derived small extracellular vesicles as a novel liquid biopsy approach Ravi Kumar Paluri, Ashish Kumar, Yixin Su, Gregory L. Kucera, Ashish Manne, Jingyun Lee, Sangeeta Sing, Susy Kim, Cristina Furdui, Gagan Deep
• 3740 · PDF OncoGraph: A patient-specific blood test using protein markers to monitor cancer recurrence and treatment response Mao Mao, Wenjian Wang, Qingqi Ren, Shiyong Li, Wei Wu
• 3741 · PDF Radiation-dendritic cell combination therapy drives systemic cellular immune shifts in liver cancer Melody Wu, Panwen Wang, Chen Wu, Ying Li, Christopher L. Hallemeier, Thomas D. Atwell, Nguyen H. Tran, Andre de Menezes Silva Corraes, Kevin Regan, Zuoyi Shao, Rayaan Kamal, Haidong Dong, Lewis R. Roberts, Sean Park, Yi Lin, Lionel Aurelien Kankeu Fonkoua
• 3742 3742 Immune microenvironment rather than genomic alterations drives hyperprogression-related features in 11q13 amplified Chinese esophageal cancer Ling Deng
• 3743 · PDF ddPLEX EGFR/KRAS/BRAF: A highly multiplexed droplet digital PCR (ddPCR) panel for ultra-sensitive NSCLC biomarker detection Surbhi Jain, Cailin Festog, Mai Ho, Cindy Li, Necip Mehmet, Ady Melendez-Molina, Toshiro Newsum, Prithwish Pal, Mina Rostamza, Yusuke Ono, Leisa Jackson, Brittany D’Alessio, Gunnar Johnson, Gary A. Pestano
• 3744 · PDF Peripheral immune indices predict pathologic complete response and residual cancer burden in inflammatory breast cancers Hui Gao, Ranjan Upadhyay, Angela Alexander, Angela N. Marx, Megumi Kai, Chelain R. Goodman, Azadeh Nasrazadani, Savitri Krishnamurthy, Anthony Lucci, Rachel M. Layman, Sadia Saleem, Vicente Valero, Michael C. Stauder, Susie X. Sun, Gary J. Whitman, Miral M. Patel, Huong C. Le-Petross, Chasity L. Yajima, Lily Villarreal, Heather Lopez, Bora Lim
• 3745 · PDF Unveiling clear cell renal cell carcinoma heterogeneity associated with locally advanced disease using single nucleus multi-omics Pratik Shah, Anita Ng, Justin Wang, Houman Khalili, Tony Pham, Melissa Neumann, Xinhua Zhu, Annette Lee, Andrew Shih
• 3746 · PDF Single-cell liquid biopsy profiling in mCRPC receiving PSCA-targeted CAR-T cell therapy Doanna Minh Pham, Stephanie Nicole Shishido, Saul J. Priceman, Tanya B. Dorff, Peter Kuhn
• 3747 · PDF Discovery and functional characterization of enhancer hijacking oncogene rearrangements in NSCLC using Hi-C sequencing of FFPE tumors Kristin Sikkink, Blake Skrable, Sid Selvaraj, Alex Hastie, Anthony Schmitt
• 3748 · PDF A proportion of shared mutations in lung squamous cell carcinoma provides insights that may guide therapeutic approaches Jaewoong Lee, Jun Hyeok Lim, Lucia Kim, Woo Kyung Ryu, Hyun-Tae Shin, In-Jae Oh, Sabin Park, Yoo Duk Choi, Semin Lee, Jeong Seon Ryu
• 3749 · PDF Integrative multiomics and functional studies to identify biomarkers of AOH1996 sensitivity across AML subtypes Hamsini Kala, Dana Abou Abbas, Robert J. Hickey, Linda H. Malkas, Caroline M. Li, Robert G. Lingeman, Guido Marcucci, Le Xuan Truong Nguyen, Brian Ball, Amanda Blackmon, Melissa Ronan, Jennifer Roth, Matthew G. Rees
• 3751 · PDF QVT Subscore: An interpretable radiomic panel of tumor vascularity reveals treatment-specific mechanisms-of-action (MoA) in NSCLC Haojia Li, Pushkar Mutha, Young Kwang Chae, Kai Zhang, Liam Il-Young Chung, Amogh Hiremath, Rhea Chitalia, Justin Yau, Omid Haji-Maghsoudi, Trishan Arul, Vamsidhar Velcheti, Anant Madabhushi, Nathaniel Braman
• 3752 · PDF RNA editing deaminase activation as a dynamic marker to track hematopoietic stem cell fitness and leukemia evolution Inge van der Werf, Jessica Pham, Neha Katragadda, Kendale Wirtjes, Athena Mohebbi, Emma Klacking, Thomas Whisenant, Ludmil B. Alexandrov, Sheldon Morris, Catriona Jamieson
• 3753 · PDF Uncovering tumor microbial and immune biomarkers of immunotherapy response in lung cancer Lili Ma, Chao Cheng, Shwetha Vasanth Kumar, Spiridon Tsavachidis, Aaron P. Thrift, Joseph F. Petrosino, Hee-Jin Jang, Robert Taylor Ripley, Christopher I. Amos, Hyun-Sung Lee, Matthew B. Schabath, David C. Christiani, Yanhong Liu

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