PO.CH02.01 · 化学
Proteomics: Biomarker Discovery and Signaling Networks
- 7677 7677 High-throughput plasma proteomics enables sarcopenia stratification and identifies the IGFBP axis as a key mediator of muscle impairment in cancer patients Filippo Gustavo Dall'Olio, Wael Salem Zrafi, Xinran Song, Littisha Lawrance, Fei Chen, Pierre Busson, Catherine Brenner, Rebecca Ibrahim, Marie Guinhut, Caroline Even, Nathalie Lassau, Diana Cardenas-Braz, Fabrice Barlesi, Yohann Loriot, Fabrice Andre, Mariam Jamal-Hanjani, Antoine Italiano, Yegor Vassetzky, Benjamin Besse
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- 7681 7681 Chemical proteomics identifies a transcription-related network of proteins that interact with the next-generation poly(ADP-ribose) polymerase inhibitor saruparib Rachael H. Martin, Lindsey Nguy, Thales Da Costa Nepomuceno, Ou Deng, John M. Koomen, Uwe Rix, Alvaro N. Monteiro
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- 7683 7683 A proteomic analysis of differential protein expression between platinum-sensitive and platinum-resistant high grade serous ovarian cancer Nujsaubnusi Cassandra Vue, Kyla Frenia, Xi Peng, Eirwen Miller, John Nakayama, Sharon Liang, Sarah Crafton, Alyssa Wield, Christopher Morse, Thomas Krivak, Qiangmin Zheng, Kunhong Xiao
- 7684 7684 Absolute quantification of 400 plasma proteins using a novel NGS-based immunoassay: Analytical validation and biomarker discovery in breast cancer David Aaron Routenberg, Evan A. Gizzie, Annamaria Szabolics, Lucie Hebert, Somnath Paul, Anthony Williams, Richard J. Cote, Jacob N. Wohlstadter
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- 7688 7688 Blood-based proteomic profiling reveals novel biomarkers of neuroendocrine prostate cancer Tatiana Erazo, Ethan S. Barnett, Amanda Weaver, A. Zara Herskovits, Alisa Valentino, Howard I. Scher, Gary A. Pestano
- 7689 7689 Absolute quantification by targeted proteomics identifies BRCA1 hypomorphs and other PARP inhibitor resistance mechanisms in patient-derived xenografts Beom-Jun Kim, Alba Llop-Guevara, Steve M. Sweet, Camille Lombard-Banek, Robert Hanson, Chris Richardson, Violeta Serra, Elizabeth A. Harrington, Josep Forment, Yeoun Jin Kim
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- 7692 7692 Proteomic analysis of immune synapses by high-precision microscopy-guided photo-biotinylation Jung-Chi Liao, Chantal Hoi Yin Cheung, Weng-Man Chong, Harry Huang, Hsiao-Jen Chang, Chia-Wen Chung
- 7693 7693 Unlocking the surfaceome: Nanoscale spatial proteomics for biomarker and target discovery using Synlight-Rich and Synlight-Pure Jung-Chi Liao, Po-Chao Chan, Weng-Man Chong, Hsiao-Jen Chang, Michelli Faria de Oliveira, Elate Huang, Daniel Dlugolenski
- 7694 7694 Proteomic analysis of BRAF-V600E mutant metastatic colorectal cancer FFPE tissues reveals potential involvement of WEE1 expression in therapeutic resistance Shotaro Yamaguchi, Satoshi Muraoka, Yosui Nojima, Toshiharu Hirose, Hidekazu Hirano, Natsuko Okita, Atsuo Takashima, Jun Adachi, Hirokazu Shoji, Ken Kato
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- 7698 7698 Advancing plasma proteomics: A next-generation nanoparticle enrichment workflow for deep and quantitative biomarker discovery in colorectal cancer Cameron Ellis, Katharina Limm, Sandra Schär, Roland Bruderer, Nils Kulak
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- 7704 7704 Proteome-wide high throughput perturbation screening of microglial response to oncologic compounds reveals distinct immunomodulation and toxicity profiles Alyssa Rosenbloom, Kiran Edwardson, Nathaniel Robichaud, Narges Rashidi, Milad Dagher
- 7705 7705 Simultaneous quantitation and discovery of cancer-related proteins in plasma using a fast, high-resolution accurate mass spectrometry-based assay provides insight into precision oncology and drug discovery Dominique Figueroa, Qingling Li, Jared Deyarmin, Sophia Steigerwald, Matthew R. Dallas, Stephanie Samra
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